The World Health Organization (WHO) states, “At the biological level, aging results from the impact of the accumulation of a wide variety of molecular and cellular damage over time.” Cellular dysfunction occurs from exposure to various physiological and metabolic stressors causing subsequent epigenetic changes. The better cells can respond to stressors, they become resilient, and overall health improves.

A growing body of published research suggests the level of a critical coenzyme called nicotinamide adenine dinucleotide (NAD+) is an important factor in cellular resilience and age-related decline. NAD+ plays an essential role in maintaining healthy mitochondrial and cellular function, activating DNA repair mechanisms, and helps to resist the effects of metabolic stressors.

The different forms of B3 vitamins serve as precursors for NAD+. Vitamin B3 is an essential nutrient that must be consumed through diet. While the RDA is sufficient to avoid pellagra, a disease caused by a lack of vitamin B3, requirements for supporting optimal health have yet to be established. A subclinical NAD+ deficiency has been hypothesized to be a common factor of aging, indicated by reduced NAD+ levels.

On Wednesday, March 3, 2021, from 2–3 PM EST, join Marie Spano, MS, RD, CSCS, CSSD, for a webinar that will provide an understanding of why and how boosting NAD supports energy production and healthy aging, and how NAD+ repletion can be attained through lifestyle methods and NAD+ precursors.