The high polyunsaturated fatty acid, or PUFA, content in the human brain makes it particularly vulnerable to the oxidative stress produced by a typical western style dietary pattern. An emerging, but compelling body of evidence demonstrates that such a dietary pattern can have deleterious effects on cognitive function, and may lead to neuro-degenerative disorders, including but not limited to Alzheimer’s disease, Parkinson’s, schizophrenia, and the like.